Across TCGA patient cohorts, ZNF669 protein abundance is significantly associated with the RNA expression of many other genes, with 278 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF669-associated genes across cancer lineages are ANXA13, CBL, and CSRNP2. Each is linked with ZNF669 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF669-to-partner and partner-to-ZNF669 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF669→partner) and Y-score (partner→ZNF669) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANXA13 →	+0.335	+1.387	<.001	.005	3	1
BRCA	CBL →	+0.374	+1.244	<.001	.001	3	1
BRCA	CSRNP2 →	+0.787	+1.662	.001	<.001	3	1
BRCA	VDR →	+0.878	+0.834	.007	.007	3	1
BRCA	CAP2 →	+1.554	+1.207	.006	.002	3	1
BRCA	EFHD1 →	+2.324	+1.645	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 278 associations by consensus.

Exploration

ZNF669 survival (RNA) · tumor vs normal (RNA) · all ZNF669 data types