Across TCGA cell cohorts, ZNF669 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,956 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF669-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Negative regulation of transcription by RNA polymerase I, and Heterochromatin formation. Each is linked with ZNF669 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF669-to-partner and partner-to-ZNF669 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF669→partner) and Y-score (partner→ZNF669) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription initiation at RNA polymerase II promoter →	+0.089	+0.969	<.001	.002	3	16
LUNG_SCLC	Negative regulation of transcription by RNA polymerase I →	+0.113	+0.780	<.001	<.001	3	15
STOMACH	Heterochromatin formation →	+0.076	+0.720	<.001	.003	3	15
STOMACH	Epigenetic regulation of gene expression →	+0.066	+0.880	.001	.004	3	15
UPPER_AERODIGESTIVE_TRACT	Nuclear pore complex assembly →	+0.198	+0.975	<.001	<.001	3	15
BONE	Nuclear pore organization →	+0.204	+1.342	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,956 associations by consensus.

Exploration

ZNF669 survival (RNA) · tumor vs normal (RNA) · all ZNF669 data types