Across TCGA cell cohorts, ZNF669 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF669-associated genes across cancer lineages are PRAMEF27 and REG1B. Each is linked with ZNF669 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF669-to-partner and partner-to-ZNF669 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF669→partner) and Y-score (partner→ZNF669) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRAMEF27 →	+0.020	+5.643	<.001	.002	3	1
LARGE_INTESTINE	REG1B →	+2.047	+3.196	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

ZNF669 survival (RNA) · tumor vs normal (RNA) · all ZNF669 data types