ZNF668

Across TCGA patient cohorts, ZNF668 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,983 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF668-associated proteins across cancer lineages are SPARC, DPYSL3, and FAP. Each is linked with ZNF668 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF668-to-partner and partner-to-ZNF668 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF668 versus SPARC in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF668→partner) and Y-score (partner→ZNF668) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPARC →	+0.629	+0.494	<.001	<.001	3	5
OV	DPYSL3 →	+0.620	+0.466	.001	.003	3	5
OV	FAP →	+0.888	+0.487	<.001	<.001	3	5
PDAC	P3H3 →	+0.587	+0.384	<.001	<.001	3	5
COAD	RCN3 →	+0.558	+0.269	.001	.006	3	4
BRCA	ISLR →	+0.644	+0.508	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,983 associations by consensus.

ZNF668 vs SPARC — OV

Explore this scatter interactively →