ZNF668

Across TCGA cell cohorts, ZNF668 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,228 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF668-associated GO terms across cancer lineages are CAMP/PKA signal transduction, Regulation of chromatin organization, and Regulation of protein localization to centrosome. Each is linked with ZNF668 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF668-to-partner and partner-to-ZNF668 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMP/PKA signal transduction grouped by ZNF668-low versus ZNF668-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF668→partner) and Y-score (partner→ZNF668) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CAMP/PKA signal transduction →	+0.146	+0.515	.002	.002	2	17
BLOOD_Myeloma	Regulation of chromatin organization →	+0.078	+0.589	<.001	.002	3	14
PANCREAS	Regulation of protein localization to centrosome →	+0.086	+0.669	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of protein localization to chromatin →	+0.126	+0.506	.002	.004	3	13
BLOOD_Lymphoma	Negative regulation of autophagosome maturation →	+0.112	+0.810	<.001	<.001	3	13
OESOPHAGUS	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.108	+0.585	.002	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,228 associations by consensus.

CAMP/PKA signal transduction by ZNF668 expression — LUNG_SCLC

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