Across TCGA cell cohorts, ZNF667 mutation is significantly associated with the drug of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF667-associated genes across cancer lineages are AZD5438, AGI-6780, and PAK_5339. Each is linked with ZNF667 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF667-to-partner and partner-to-ZNF667 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF667→partner) and Y-score (partner→ZNF667) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD5438 →	+0.451	+3.192	.044	.007	3	1
LARGE_INTESTINE	AGI-6780 →	+0.386	+3.061	.027	.010	3	1
LARGE_INTESTINE	PAK_5339 →	+0.303	+2.678	.025	.037	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.518	+2.710	.030	.027	3	1
LARGE_INTESTINE	SGC0946 →	+0.268	+2.932	.048	.019	3	1
LARGE_INTESTINE	Brivanib →	+0.371	+3.067	.018	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

ZNF667 survival (RNA) · tumor vs normal (RNA) · all ZNF667 data types