ZNF665

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF665 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF665-associated genes across cancer lineages are EGFR_pY1068, TIGAR, and 4E-BP1_pT70. Each is linked with ZNF665 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF665-to-partner and partner-to-ZNF665 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF665→partner) and Y-score (partner→ZNF665) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.276-2.201.001<.00133
UCECTIGAR →+0.117+1.901.022.00133
COAD4E-BP1_pT70 →+0.134+2.815.041.03632
COADC-Raf →+0.229+2.815.004.03632
UCEC14-3-3_beta →-0.095-2.973.004<.00132
UCECA-Raf_pS299 →-0.130-2.000.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration