Across TCGA patient cohorts, ZNF663P mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF663P-associated genes across cancer lineages are EGFR_pY1068, ACC_pS79, and ACC1. Each is linked with ZNF663P in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF663P-to-partner and partner-to-ZNF663P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF663P→partner) and Y-score (partner→ZNF663P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.330	-3.459	.008	.005	3	1
UCEC	ACC_pS79 →	+0.448	+2.321	.010	.035	3	1
UCEC	ACC1 →	+0.514	+2.321	.004	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.220	-3.169	.009	.018	3	1
UCEC	AMPK_alpha →	-0.207	-3.000	.030	.036	3	1
UCEC	S6_pS240_S244 →	+0.588	+2.321	.003	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ZNF663P survival (RNA) · tumor vs normal (RNA) · all ZNF663P data types