ZNF660

Across TCGA cell cohorts, ZNF660 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,521 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF660-associated GO terms across cancer lineages are Protein-DNA complex organization, Heterochromatin formation, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNF660 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF660-to-partner and partner-to-ZNF660 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by ZNF660-low versus ZNF660-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF660→partner) and Y-score (partner→ZNF660) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein-DNA complex organization →	+0.071	+1.048	<.001	<.001	3	12
SOFT_TISSUE	Heterochromatin formation →	+0.069	+1.109	<.001	<.001	3	11
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.075	+0.784	<.001	<.001	3	11
OVARY	Cytoplasmic translation →	+0.079	+0.529	<.001	.002	3	11
OVARY	Regulation of myoblast fusion →	+0.088	+0.577	<.001	.001	3	10
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.074	+0.785	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,521 associations by consensus.

Protein-DNA complex organization by ZNF660 expression — SOFT_TISSUE

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