ZNF66

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF66 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF66-associated genes across cancer lineages are Notch1. Each is linked with ZNF66 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF66-to-partner and partner-to-ZNF66 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by ZNF66-low versus ZNF66-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF66→partner) and Y-score (partner→ZNF66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.261+2.820.002.03531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Notch1 by ZNF66 expression — UCEC

Box plot of Notch1 in ZNF66-low vs ZNF66-high samples in UCEC.

Explore this box plot interactively →

Exploration