ZNF658B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF658B mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF658B-associated genes across cancer lineages are EGFR_pY1068, JNK2, and p38-MAPK_pT180_Y182. Each is linked with ZNF658B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF658B-to-partner and partner-to-ZNF658B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF658B→partner) and Y-score (partner→ZNF658B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.244-2.222.002.00932
UCECJNK2 →+0.210+1.523<.001.00832
UCECp38-MAPK_pT180_Y182 →-0.312-1.276.030.02332
UCECSTAT3_pY705 →-0.338-1.523<.001.00832
UCECTFRC →+0.544+3.700.001.00132
UCECATM →-0.659-2.986<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

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