Across TCGA patient cohorts, ZNF655 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF655-associated genes across cancer lineages are Akt_pT308, STAT3_pY705, and Tuberin_pT1462. Each is linked with ZNF655 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF655-to-partner and partner-to-ZNF655 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF655→partner) and Y-score (partner→ZNF655) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Akt_pT308 →	+0.416	+2.000	.049	.029	3	3
UCEC	STAT3_pY705 →	-0.376	-2.311	<.001	<.001	3	2
UCEC	Tuberin_pT1462 →	+0.236	+1.807	.002	.024	3	2
UCEC	ASNS →	+0.415	+1.700	<.001	.040	3	2
UCEC	eEF2K →	+0.234	+2.115	.045	.017	3	2
UCEC	14-3-3_beta →	-0.091	-2.088	.007	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

ZNF655 survival (RNA) · tumor vs normal (RNA) · all ZNF655 data types