ZNF654

Across TCGA cell cohorts, ZNF654 RNA expression is significantly associated with the RNA expression of many other genes, with 9,805 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF654-associated genes across cancer lineages are CGGBP1, C3orf38, and PPP4R2. Each is linked with ZNF654 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZNF654-to-partner and partner-to-ZNF654 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF654 versus CGGBP1 in OESOPHAGUS, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF654→partner) and Y-score (partner→ZNF654) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CGGBP1 →	+1.182	+0.995	<.001	<.001	3	20
STOMACH	C3orf38 →	+1.164	+1.092	<.001	.001	3	19
STOMACH	PPP4R2 →	+1.055	+1.071	<.001	<.001	3	16
OESOPHAGUS	CHMP2B →	+1.117	+0.797	.002	<.001	3	14
BREAST	TMF1 →	+0.862	+0.681	<.001	.001	1	15
STOMACH	RYBP →	+1.158	+0.884	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,805 associations by consensus.

ZNF654 vs CGGBP1 — OESOPHAGUS

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