Across TCGA patient cohorts, ZNF649 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,870 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF649-associated proteins across cancer lineages are RNF213, SEC63, and BCAP31. Each is linked with ZNF649 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF649-to-partner and partner-to-ZNF649 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF649→partner) and Y-score (partner→ZNF649) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNF213 →	-0.417	-0.366	<.001	.003	3	5
CCRCC	SEC63 →	-0.324	-0.402	<.001	<.001	3	5
UCEC	BCAP31 →	-0.554	-0.498	.001	<.001	3	5
GBM	PARP4 →	-0.549	-0.686	<.001	<.001	3	5
CCRCC	PTPN1 →	-0.355	-0.407	<.001	<.001	3	5
GBM	GNL1 →	+0.164	+0.568	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,870 associations by consensus.

Exploration

ZNF649 survival (RNA) · tumor vs normal (RNA) · all ZNF649 data types