Across TCGA patient cohorts, ZNF649 mutation is significantly associated with the RNA expression of many other genes, with 2,498 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF649-associated genes across cancer lineages are LINC01853, MIR648, and RNA5SP413. Each is linked with ZNF649 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF649-to-partner and partner-to-ZNF649 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF649→partner) and Y-score (partner→ZNF649) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC01853 →	+0.326	+4.888	<.001	.005	3	3
LUSC	MIR648 →	+0.621	+4.890	<.001	<.001	3	3
UCEC	RNA5SP413 →	+0.852	+1.762	<.001	<.001	3	3
CESC	VN1R7P →	+0.090	+4.874	<.001	.002	3	2
LUAD	NF1P10 →	+0.459	+4.554	<.001	.009	3	2
SKCM	LMF2 →	+0.603	+3.228	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,498 associations by consensus.

Exploration

ZNF649 survival (RNA) · tumor vs normal (RNA) · all ZNF649 data types