Across TCGA cell cohorts, ZNF649 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,687 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF649-associated GO terms across cancer lineages are Regulation of RNA splicing, RNA export from nucleus, and Positive regulation of cytoplasmic translation. Each is linked with ZNF649 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF649-to-partner and partner-to-ZNF649 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF649→partner) and Y-score (partner→ZNF649) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of RNA splicing →	+0.092	+1.584	<.001	<.001	3	13
STOMACH	RNA export from nucleus →	+0.104	+1.691	.003	.003	3	13
OESOPHAGUS	Positive regulation of cytoplasmic translation →	+0.126	+1.202	<.001	.003	3	12
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.059	+1.413	.005	.003	2	12
SOFT_TISSUE	Regulation of mRNA processing →	+0.101	+1.167	<.001	.001	3	11
SOFT_TISSUE	Nuclear transport →	+0.076	+1.210	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Exploration

ZNF649 survival (RNA) · tumor vs normal (RNA) · all ZNF649 data types