ZNF648

Across TCGA cell cohorts, ZNF648 RNA expression is significantly associated with the go_rna of many other GO terms, with 517 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF648-associated GO terms across cancer lineages are Regulation of fertilization, Vesicle-mediated transport between endosomal compartments, and Early endosome to late endosome transport. Each is linked with ZNF648 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF648-to-partner and partner-to-ZNF648 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fertilization grouped by ZNF648-low versus ZNF648-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF648→partner) and Y-score (partner→ZNF648) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of fertilization →	-0.181	-0.078	<.001	.005	2	5
BREAST	Vesicle-mediated transport between endosomal compartments →	+0.053	+0.072	<.001	<.001	3	4
BREAST	Early endosome to late endosome transport →	+0.053	+0.072	<.001	<.001	3	4
OVARY	Regulation of smooth muscle contraction →	-0.121	-0.101	<.001	.001	3	4
STOMACH	Negative regulation of negative chemotaxis →	+1.069	+0.111	<.001	.008	3	4
OVARY	Regulation of leukocyte migration →	-0.069	-0.182	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

Regulation of fertilization by ZNF648 expression — BREAST

Explore this box plot interactively →