ZNF639

Across TCGA patient cohorts, ZNF639 protein abundance is significantly associated with the RNA expression of many other genes, with 9,417 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF639-associated genes across cancer lineages are XPO1, ACVR2B, and TUT4. Each is linked with ZNF639 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF639-to-partner and partner-to-ZNF639 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF639 versus XPO1 in OV, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF639→partner) and Y-score (partner→ZNF639) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	XPO1 →	+0.838	+0.773	<.001	.003	3	4
HNSC	ACVR2B →	+0.763	+0.341	<.001	<.001	3	4
GBM	TUT4 →	+0.474	+0.339	<.001	<.001	3	4
UCEC	LRCH3 →	+0.493	+0.340	.001	<.001	3	4
LSCC	RNU6-142P →	+0.918	+0.286	.002	<.001	3	4
BRCA	CHTF18 →	+0.693	+0.327	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,417 associations by consensus.

ZNF639 vs XPO1 — OV

Explore this scatter interactively →