ZNF639

Across TCGA cell cohorts, ZNF639 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,411 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF639-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Somatic cell DNA recombination, and Somatic recombination of immunoglobulin gene segments. Each is linked with ZNF639 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF639-to-partner and partner-to-ZNF639 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by ZNF639-low versus ZNF639-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF639→partner) and Y-score (partner→ZNF639) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Establishment of mitotic sister chromatid cohesion →	+0.146	+0.829	<.001	.001	3	16
LARGE_INTESTINE	Somatic cell DNA recombination →	+0.083	+0.785	<.001	.001	3	14
LUNG_SCLC	Somatic recombination of immunoglobulin gene segments →	+0.064	+0.538	.006	.006	3	14
LARGE_INTESTINE	Somatic diversification of immune receptors via germline recombination within a single locus →	+0.083	+0.785	<.001	.001	3	14
CNS	Maintenance of centrosome location →	+0.076	+0.387	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.164	+0.688	<.001	.008	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,411 associations by consensus.

Establishment of mitotic sister chromatid cohesion by ZNF639 expression — OVARY

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