ZNF638

Across TCGA patient cohorts, ZNF638 protein abundance is significantly associated with the RNA expression of many other genes, with 20,391 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF638-associated genes across cancer lineages are POLR1C, F13A1, and VSIG4. Each is linked with ZNF638 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF638-to-partner and partner-to-ZNF638 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF638 versus POLR1C in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF638→partner) and Y-score (partner→ZNF638) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POLR1C →	+0.699	+0.318	<.001	<.001	3	8
GBM	F13A1 →	-1.420	-0.227	<.001	<.001	3	7
GBM	VSIG4 →	-1.240	-0.284	<.001	<.001	3	7
BRCA	FOLR2 →	-0.899	-0.186	<.001	<.001	3	7
GBM	CD14 →	-1.025	-0.250	<.001	<.001	3	7
HNSC	C14orf93 →	+0.678	+0.300	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,391 associations by consensus.

ZNF638 vs POLR1C — HNSC

Explore this scatter interactively →