ZNF638

Across TCGA cell cohorts, ZNF638 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,627 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF638-associated GO terms across cancer lineages are Regulation of RNA splicing, Negative regulation of gene expression, epigenetic, and Peptidyl-lysine modification. Each is linked with ZNF638 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF638-to-partner and partner-to-ZNF638 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by ZNF638-low versus ZNF638-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF638→partner) and Y-score (partner→ZNF638) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of RNA splicing →	+0.092	+0.731	<.001	<.001	3	17
STOMACH	Negative regulation of gene expression, epigenetic →	+0.079	+0.562	<.001	.005	3	16
STOMACH	Peptidyl-lysine modification →	+0.050	+0.575	.001	<.001	3	16
OVARY	Spliceosomal complex assembly →	+0.092	+0.794	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.124	+0.859	<.001	<.001	3	16
STOMACH	Heterochromatin formation →	+0.078	+0.562	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,627 associations by consensus.

Regulation of RNA splicing by ZNF638 expression — SOFT_TISSUE

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