ZNF638

Across TCGA cell cohorts, ZNF638 mutation is significantly associated with the RNA expression of many other genes, with 896 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF638-associated genes across cancer lineages are HACE1, OR4C6, and ZBED4. Each is linked with ZNF638 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF638-to-partner and partner-to-ZNF638 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HACE1 grouped by ZNF638-low versus ZNF638-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF638→partner) and Y-score (partner→ZNF638) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HACE1 →	+0.690	+3.234	.003	.004	3	3
BREAST	OR4C6 →	+0.323	+4.199	.001	.007	3	2
LARGE_INTESTINE	ZBED4 →	+0.428	+3.459	.008	.001	3	2
LARGE_INTESTINE	ZC3H14 →	+0.408	+2.459	.006	.006	3	2
LARGE_INTESTINE	CEP76 →	+0.579	+3.321	.002	.002	3	2
LARGE_INTESTINE	PRDM4 →	+0.457	+2.451	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 896 associations by consensus.

HACE1 by ZNF638 expression — LARGE_INTESTINE

Explore this box plot interactively →