ZNF630

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF630 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF630-associated genes across cancer lineages are eEF2, EGFR_pY1068, and eIF4E. Each is linked with ZNF630 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF630-to-partner and partner-to-ZNF630 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF630→partner) and Y-score (partner→ZNF630) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.293+2.807.006.00232
UCECEGFR_pY1068 →-0.244-2.247.001.00132
UCECeIF4E →+0.223+1.999<.001<.00132
UCECJNK2 →+0.301+2.584<.001<.00132
UCECp53 →-0.312-2.222.007.00932
UCECp62 Lck ligand →+0.374+1.999<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration