ZNF629

Across TCGA patient cohorts, ZNF629 mutation is significantly associated with the RNA expression of many other genes, with 2,366 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF629-associated genes across cancer lineages are SAP30, UIMC1, and CBARP. Each is linked with ZNF629 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF629-to-partner and partner-to-ZNF629 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAP30 grouped by ZNF629-low versus ZNF629-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF629→partner) and Y-score (partner→ZNF629) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SAP30 →	+0.571	+3.472	.002	.002	3	3
UCEC	UIMC1 →	+0.421	+2.201	<.001	<.001	3	3
UCEC	CBARP →	+0.827	+3.058	<.001	<.001	3	3
COAD	TLE6 →	+0.848	+3.486	<.001	.002	3	3
KIRP	RNU6-939P →	+0.443	+5.770	<.001	.003	3	3
UCEC	ADAM33 →	-0.820	-2.574	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,366 associations by consensus.

SAP30 by ZNF629 expression — COAD

Explore this box plot interactively →