ZNF629

Across TCGA cell cohorts, ZNF629 mutation is significantly associated with the RNA expression of many other genes, with 1,651 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF629-associated genes across cancer lineages are KSR2, ASB17, and KCTD1. Each is linked with ZNF629 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF629-to-partner and partner-to-ZNF629 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KSR2 grouped by ZNF629-low versus ZNF629-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF629→partner) and Y-score (partner→ZNF629) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KSR2 →	+0.289	+3.798	.003	.004	3	2
STOMACH	ASB17 →	+0.028	+3.432	<.001	.008	3	2
LARGE_INTESTINE	KCTD1 →	+0.841	+1.850	.005	.006	3	2
LARGE_INTESTINE	MGARP →	+0.104	+3.339	.001	.001	3	2
LARGE_INTESTINE	ABCG4 →	+0.173	+2.188	.002	.001	3	2
LARGE_INTESTINE	MSH4 →	+0.221	+2.463	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,651 associations by consensus.

KSR2 by ZNF629 expression — BLOOD_Leukemia

Explore this box plot interactively →