Across TCGA patient cohorts, ZNF627 mutation is significantly associated with the RNA expression of many other genes, with 2,484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF627-associated genes across cancer lineages are RNA5SP161, FAM177A1, and XPC. Each is linked with ZNF627 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF627-to-partner and partner-to-ZNF627 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF627→partner) and Y-score (partner→ZNF627) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP161 →	+0.249	+5.342	<.001	.002	3	2
UCEC	FAM177A1 →	+0.426	+3.939	<.001	<.001	3	2
UCEC	XPC →	+0.477	+1.818	.002	.002	3	2
UCEC	WHAMM →	+0.537	+3.119	<.001	<.001	3	2
UCEC	C12orf43 →	+0.328	+3.774	<.001	<.001	3	2
UCEC	ANXA5 →	+0.459	+2.534	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,484 associations by consensus.

Exploration

ZNF627 survival (RNA) · tumor vs normal (RNA) · all ZNF627 data types