Across TCGA cell cohorts, ZNF627 mutation is significantly associated with the drug of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF627-associated genes across cancer lineages are IAP_5620, Fulvestrant, and Dinaciclib. Each is linked with ZNF627 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF627-to-partner and partner-to-ZNF627 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF627→partner) and Y-score (partner→ZNF627) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IAP_5620 →	+0.395	+2.649	.032	.046	3	1
LARGE_INTESTINE	Fulvestrant →	+0.377	+2.649	.027	.046	3	1
LARGE_INTESTINE	Dinaciclib →	+0.518	+2.646	.044	.047	1	1
LARGE_INTESTINE	AZD5582 →	+0.709	+2.646	.014	.047	1	1
LARGE_INTESTINE	Entospletinib →	+0.496	+2.646	.008	.047	1	1
LARGE_INTESTINE	CDK9_5038 →	+0.631	+2.906	.021	.033	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ZNF627 survival (RNA) · tumor vs normal (RNA) · all ZNF627 data types