Across TCGA pan-cancer cohorts, ZNF626 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ZNF626 data layer compared with 20 for mass-spec protein.
The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ZNF626 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF626 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCEC show a favorable association.
STAD, SKCM, and UCEC are the cancer types where ZNF626 Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.