Across TCGA patient cohorts, ZNF626 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF626-associated genes across cancer lineages are JNK_pT183_Y185, 4E-BP1, and FASN. Each is linked with ZNF626 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF626-to-partner and partner-to-ZNF626 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF626→partner) and Y-score (partner→ZNF626) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.121	-1.723	.037	.007	3	3
UCEC	4E-BP1 →	+0.325	+3.730	<.001	<.001	3	3
UCEC	FASN →	+0.297	+1.440	.030	.024	3	2
UCEC	mTOR_pS2448 →	-0.159	-2.395	.002	.003	3	2
UCEC	PCNA →	+0.195	+1.906	.009	.015	3	2
UCEC	Shc_pY317 →	-0.149	-1.440	.004	.024	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

ZNF626 survival (RNA) · tumor vs normal (RNA) · all ZNF626 data types