ZNF625

Across TCGA cell cohorts, ZNF625 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF625-associated genes across cancer lineages are C16orf92, ADAMTS19, and DAZ4. Each is linked with ZNF625 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF625-to-partner and partner-to-ZNF625 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C16orf92 grouped by ZNF625-low versus ZNF625-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF625→partner) and Y-score (partner→ZNF625) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C16orf92 →	+0.056	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ADAMTS19 →	+0.665	+3.541	.003	.004	3	1
LARGE_INTESTINE	DAZ4 →	+0.123	+3.240	.004	.004	3	1
LUNG_NSCLC_LUAD	OR52B4 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	RBMY1B →	+0.734	+4.887	<.001	.009	3	1
LARGE_INTESTINE	ASPN →	+0.032	+3.648	.008	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C16orf92 by ZNF625 expression — SKIN

Explore this box plot interactively →