Across TCGA cell cohorts, ZNF624 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF624-associated genes across cancer lineages are MMD2, RAI1, and MAGEB4. Each is linked with ZNF624 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF624-to-partner and partner-to-ZNF624 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF624→partner) and Y-score (partner→ZNF624) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	MMD2 →	+0.063	+5.087	<.001	.004	3	1
LARGE_INTESTINE	RAI1 →	+0.994	+3.064	.001	.009	3	1
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	KDM3B →	+0.542	+3.067	.002	.009	3	1
LARGE_INTESTINE	NHP2 →	+0.485	+3.067	.006	.009	3	1
LARGE_INTESTINE	ZAN →	+0.007	+2.560	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

ZNF624 survival (RNA) · tumor vs normal (RNA) · all ZNF624 data types