ZNF623

Across TCGA patient cohorts, ZNF623 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,057 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF623-associated proteins across cancer lineages are SCRIB, PTK2, and PYCR3. Each is linked with ZNF623 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF623-to-partner and partner-to-ZNF623 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF623 versus SCRIB in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF623→partner) and Y-score (partner→ZNF623) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SCRIB →	+0.419	+0.665	<.001	<.001	3	10
LUAD	PTK2 →	+0.450	+0.625	<.001	<.001	3	8
LSCC	PYCR3 →	+0.417	+0.561	<.001	<.001	3	7
OV	C8orf82 →	+0.571	+0.761	.002	<.001	3	7
OV	HSF1 →	+0.718	+0.755	.008	.004	3	7
GBM	WDR5 →	+0.243	+0.235	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,057 associations by consensus.

ZNF623 vs SCRIB — LSCC

Explore this scatter interactively →