ZNF623

Across TCGA patient cohorts, ZNF623 protein abundance is significantly associated with the RNA expression of many other genes, with 5,773 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF623-associated genes across cancer lineages are HNF4G, BTLA, and RNU6-838P. Each is linked with ZNF623 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF623-to-partner and partner-to-ZNF623 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF623 versus HNF4G in UCEC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF623→partner) and Y-score (partner→ZNF623) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HNF4G →	-1.815	-0.253	.002	<.001	3	2
UCEC	BTLA →	-2.611	-0.267	.002	.003	3	2
UCEC	RNU6-838P →	-2.364	-0.253	<.001	.001	3	2
LSCC	LINC00526 →	+0.655	+0.384	.005	.009	3	2
UCEC	TXK →	-1.881	-0.321	<.001	<.001	3	2
LSCC	CEBPE →	-0.275	-0.286	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,773 associations by consensus.

ZNF623 vs HNF4G — UCEC

Explore this scatter interactively →