ZNF623

Across TCGA patient cohorts, ZNF623 mutation is significantly associated with the RNA expression of many other genes, with 3,432 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF623-associated genes across cancer lineages are ZNF330, DCLRE1B, and COPS3. Each is linked with ZNF623 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF623-to-partner and partner-to-ZNF623 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF330 grouped by ZNF623-low versus ZNF623-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF623→partner) and Y-score (partner→ZNF623) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF330 →	+0.319	+2.705	.002	<.001	3	3
COAD	DCLRE1B →	+0.443	+3.469	.001	.002	3	3
UCEC	COPS3 →	+0.443	+1.632	<.001	<.001	3	3
COAD	C18orf54 →	+0.465	+2.605	.001	.005	3	3
COAD	ING2 →	+0.435	+2.700	.001	.006	3	3
UCEC	RAD51 →	+0.646	+1.642	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,432 associations by consensus.

ZNF330 by ZNF623 expression — UCEC

Explore this box plot interactively →