ZNF623

Across TCGA cell cohorts, ZNF623 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,264 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF623-associated GO terms across cancer lineages are Negative regulation of macroautophagy, Positive regulation of mRNA metabolic process, and RNA export from nucleus. Each is linked with ZNF623 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF623-to-partner and partner-to-ZNF623 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of macroautophagy grouped by ZNF623-low versus ZNF623-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF623→partner) and Y-score (partner→ZNF623) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of macroautophagy →	+0.094	+0.800	<.001	.003	3	15
SOFT_TISSUE	Positive regulation of mRNA metabolic process →	+0.066	+0.705	<.001	<.001	3	15
BLOOD_Lymphoma	RNA export from nucleus →	+0.107	+1.089	<.001	<.001	3	15
STOMACH	miRNA processing →	+0.090	+0.985	.002	<.001	3	15
BLOOD_Myeloma	Negative regulation of translational initiation →	+0.124	+0.883	<.001	.008	3	15
SOFT_TISSUE	P-body assembly →	+0.104	+0.498	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,264 associations by consensus.

Negative regulation of macroautophagy by ZNF623 expression — BLOOD_Myeloma

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