ZNF620

Across TCGA patient cohorts, ZNF620 mutation is significantly associated with the RNA expression of many other genes, with 758 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF620-associated genes across cancer lineages are RPS2P25, TMEM132D-AS1, and LINC02726. Each is linked with ZNF620 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF620-to-partner and partner-to-ZNF620 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS2P25 grouped by ZNF620-low versus ZNF620-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF620→partner) and Y-score (partner→ZNF620) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPS2P25 →	+0.149	+4.409	<.001	.006	3	2
CESC	TMEM132D-AS1 →	+0.494	+4.364	.007	.006	3	2
BLCA	LINC02726 →	+0.204	+3.432	<.001	.002	3	2
CESC	LINC02293 →	+0.137	+5.786	<.001	<.001	3	2
CESC	LINC02588 →	+0.343	+4.816	<.001	.003	3	2
CESC	RAC1P9 →	+0.159	+4.812	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 758 associations by consensus.

RPS2P25 by ZNF620 expression — CESC

Explore this box plot interactively →