ZNF619

Across TCGA patient cohorts, ZNF619 mutation is significantly associated with the RNA expression of many other genes, with 3,777 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF619-associated genes across cancer lineages are MIR3135A, PGGT1BP2, and BPY2DP. Each is linked with ZNF619 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF619-to-partner and partner-to-ZNF619 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3135A grouped by ZNF619-low versus ZNF619-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF619→partner) and Y-score (partner→ZNF619) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR3135A →	+0.493	+4.503	<.001	.005	3	2
COAD	PGGT1BP2 →	+0.113	+3.199	.001	.005	3	2
COAD	BPY2DP →	+0.199	+5.087	<.001	.002	3	2
UCEC	RDH13 →	+0.325	+3.721	.006	<.001	3	2
UCEC	UQCRH →	+0.697	+3.939	.006	<.001	3	2
UCEC	EIF3F →	+0.399	+2.856	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,777 associations by consensus.

MIR3135A by ZNF619 expression — CESC

Explore this box plot interactively →