ZNF619

Across TCGA cell cohorts, ZNF619 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,478 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF619-associated GO terms across cancer lineages are Regulation of mRNA catabolic process, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with ZNF619 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF619-to-partner and partner-to-ZNF619 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA catabolic process grouped by ZNF619-low versus ZNF619-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF619→partner) and Y-score (partner→ZNF619) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of mRNA catabolic process →	+0.051	+0.667	<.001	.001	3	11
KIDNEY	Regulation of myoblast fusion →	+0.079	+0.606	<.001	<.001	3	10
KIDNEY	Negative regulation of myoblast fusion →	+0.076	+0.577	<.001	<.001	3	10
SOFT_TISSUE	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.065	+0.718	<.001	<.001	3	10
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.088	+0.614	.001	.001	3	10
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.078	+0.561	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,478 associations by consensus.

Regulation of mRNA catabolic process by ZNF619 expression — KIDNEY

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