ZNF619

Across TCGA cell cohorts, ZNF619 mutation is significantly associated with the mutation status of many other genes, with 4,688 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF619-associated genes across cancer lineages are AKNAD1, QSER1, and MAST4. Each is linked with ZNF619 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF619-to-partner and partner-to-ZNF619 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKNAD1 grouped by ZNF619-low versus ZNF619-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF619→partner) and Y-score (partner→ZNF619) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AKNAD1 →	+4.215	+3.874	<.001	<.001	1	4
OVARY	QSER1 →	+4.415	+4.977	.007	.007	1	3
LARGE_INTESTINE	MAST4 →	+1.799	+3.769	.002	.002	1	3
LARGE_INTESTINE	ABCC9 →	+2.215	+3.247	.003	.003	1	3
OVARY	ASNS →	+4.415	+4.977	.007	.007	1	3
LARGE_INTESTINE	PTPN21 →	+2.215	+4.169	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,688 associations by consensus.

AKNAD1 by ZNF619 expression — LARGE_INTESTINE

Explore this box plot interactively →