ZNF618

Across TCGA patient cohorts, ZNF618 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,435 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF618-associated proteins across cancer lineages are ZNF618_S429, BRD3, and SPIN1. Each is linked with ZNF618 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF618-to-partner and partner-to-ZNF618 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF618 versus ZNF618_S429 in GBM, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF618→partner) and Y-score (partner→ZNF618) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF618_S429 →	+0.607	+0.983	<.001	<.001	3	6
LSCC	BRD3 →	+0.268	+0.517	.007	.003	3	5
LSCC	SPIN1 →	+0.295	+0.507	<.001	<.001	3	5
HNSC	BRD3_S563 →	+0.444	+0.745	.007	.001	3	4
GBM	SLTM →	+0.230	+0.453	<.001	.001	3	4
HNSC	CPTP →	-0.320	-0.759	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,435 associations by consensus.

ZNF618 vs ZNF618_S429 — GBM

Explore this scatter interactively →