ZNF618

Across TCGA cell cohorts, ZNF618 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,265 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF618-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Nucleic acid transport, and RNA transport. Each is linked with ZNF618 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF618-to-partner and partner-to-ZNF618 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by ZNF618-low versus ZNF618-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF618→partner) and Y-score (partner→ZNF618) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of nucleotide-excision repair →	+0.120	+1.337	<.001	.005	3	17
LUNG_NSCLC_LUSC	Nucleic acid transport →	+0.106	+2.021	<.001	<.001	3	16
LUNG_NSCLC_LUSC	RNA transport →	+0.106	+2.021	<.001	<.001	3	16
BREAST	Regulation of transcription initiation by RNA polymerase II →	+0.068	+1.309	<.001	.001	3	15
LUNG_NSCLC_LUSC	Heterochromatin formation →	+0.063	+1.644	.001	.002	3	15
OESOPHAGUS	Cell division →	+0.101	+1.491	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,265 associations by consensus.

Regulation of nucleotide-excision repair by ZNF618 expression — BONE

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