Across TCGA patient cohorts, ZNF616 mutation is significantly associated with the RNA expression of many other genes, with 3,978 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF616-associated genes across cancer lineages are ZMYND19, TPRN, and SAPCD2. Each is linked with ZNF616 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF616-to-partner and partner-to-ZNF616 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF616→partner) and Y-score (partner→ZNF616) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZMYND19 →	+0.429	+1.572	<.001	<.001	3	3
LUSC	TPRN →	+0.503	+3.357	.009	.005	3	3
LUSC	SAPCD2 →	+0.995	+2.620	.001	.006	3	3
UCEC	BCL2L2-PABPN1 →	+0.195	+1.980	.001	.007	3	3
UCEC	ETFA →	+0.672	+2.362	<.001	<.001	3	3
UCEC	DOC2B →	-0.819	-1.785	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,978 associations by consensus.

Exploration

ZNF616 survival (RNA) · tumor vs normal (RNA) · all ZNF616 data types