Across TCGA patient cohorts, ZNF616 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF616-associated genes across cancer lineages are STAT3_pY705, eIF4E, and FoxM1. Each is linked with ZNF616 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF616-to-partner and partner-to-ZNF616 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF616→partner) and Y-score (partner→ZNF616) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.333	-1.716	<.001	.002	3	3
UCEC	eIF4E →	+0.161	+2.820	.009	.001	3	2
UCEC	FoxM1 →	+0.156	+1.241	.041	.015	3	2
UCEC	MEK1 →	+0.413	+1.857	<.001	<.001	3	2
UCEC	Notch1 →	+0.109	+2.009	.008	.005	3	2
COAD	PCNA →	+0.293	+3.008	.022	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

ZNF616 survival (RNA) · tumor vs normal (RNA) · all ZNF616 data types