ZNF614

Across TCGA patient cohorts, ZNF614 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,116 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF614-associated proteins across cancer lineages are TRIM28, WRNIP1, and BICRA_S1413. Each is linked with ZNF614 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF614-to-partner and partner-to-ZNF614 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF614 versus TRIM28 in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF614→partner) and Y-score (partner→ZNF614) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.410	+0.556	<.001	<.001	3	7
GBM	WRNIP1 →	+0.342	+0.451	<.001	<.001	3	6
LUAD	BICRA_S1413 →	+0.466	+0.525	<.001	<.001	3	5
LSCC	ADNP →	+0.441	+0.589	<.001	<.001	3	5
UCEC	STIM1 →	-0.607	-0.468	<.001	<.001	2	6
OV	STRN4 →	+0.254	+0.641	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,116 associations by consensus.

ZNF614 vs TRIM28 — GBM

Explore this scatter interactively →