ZNF614

Across TCGA patient cohorts, ZNF614 protein abundance is significantly associated with the RNA expression of many other genes, with 189 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF614-associated genes across cancer lineages are ICAM5, SETX, and HIPK3. Each is linked with ZNF614 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF614-to-partner and partner-to-ZNF614 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF614 versus ICAM5 in GBM, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF614→partner) and Y-score (partner→ZNF614) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ICAM5 →	+2.616	+1.239	.005	.003	3	1
GBM	SETX →	-0.294	-0.998	.002	.001	3	1
GBM	HIPK3 →	-0.706	-0.998	<.001	.001	3	1
GBM	PTPN5 →	+3.195	+1.239	.005	.003	3	1
GBM	CREBL2 →	-0.913	-0.998	.002	.001	3	1
GBM	WIPF1 →	-1.134	-0.998	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 189 associations by consensus.

ZNF614 vs ICAM5 — GBM

Explore this scatter interactively →