ZNF614

Across TCGA cell cohorts, ZNF614 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,931 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF614-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Establishment of RNA localization, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with ZNF614 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF614-to-partner and partner-to-ZNF614 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by ZNF614-low versus ZNF614-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF614→partner) and Y-score (partner→ZNF614) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of RNA export from nucleus →	+0.119	+0.557	.003	<.001	3	12
BONE	Establishment of RNA localization →	+0.109	+0.504	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of double-strand break repair via homologous recombination →	+0.085	+0.535	<.001	.001	3	11
SOFT_TISSUE	Regulation of RNA splicing →	+0.101	+0.940	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of organelle assembly →	+0.058	+0.651	<.001	<.001	3	11
BONE	Positive regulation of cytoplasmic translation →	+0.114	+0.759	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,931 associations by consensus.

Negative regulation of RNA export from nucleus by ZNF614 expression — BONE

Explore this box plot interactively →