ZNF613

Across TCGA patient cohorts, ZNF613 mutation is significantly associated with the RNA expression of many other genes, with 710 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF613-associated genes across cancer lineages are TRBV10-1, TRAJ12, and LINC01937. Each is linked with ZNF613 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF613-to-partner and partner-to-ZNF613 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBV10-1 grouped by ZNF613-low versus ZNF613-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF613→partner) and Y-score (partner→ZNF613) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRBV10-1 →	+0.325	+3.545	.004	.006	3	2
CESC	TRAJ12 →	+0.402	+3.023	.007	.008	3	2
COAD	LINC01937 →	+0.089	+4.375	<.001	.001	3	2
UCEC	RNA5SP248 →	+0.276	+1.697	.001	.006	3	2
UCEC	TRAJ43 →	+0.669	+1.988	<.001	.001	3	2
UCEC	IGHD1-26 →	+0.551	+2.636	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 710 associations by consensus.

TRBV10-1 by ZNF613 expression — CESC

Explore this box plot interactively →