ZNF613

Across TCGA cell cohorts, ZNF613 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZNF613-associated genes across cancer lineages are IL2, NAT8B, and SSX7. Each is linked with ZNF613 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF613-to-partner and partner-to-ZNF613 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL2 grouped by ZNF613-low versus ZNF613-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF613→partner) and Y-score (partner→ZNF613) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IL2 →	+0.034	+3.700	<.001	.009	3	1
LARGE_INTESTINE	NAT8B →	+0.759	+3.295	.001	.009	3	1
STOMACH	SSX7 →	+0.325	+4.285	<.001	.007	3	1
STOMACH	RD3L →	+0.039	+4.129	.001	.007	3	1
BREAST	FAM9A →	+0.049	+5.169	<.001	.005	3	1
CNS	OR4B1 →	+0.023	+6.357	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

IL2 by ZNF613 expression — LARGE_INTESTINE

Explore this box plot interactively →