Across TCGA patient cohorts, ZNF611 mutation is significantly associated with the RNA expression of many other genes, with 2,707 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF611-associated genes across cancer lineages are LSM3, TAF9, and CCDC3. Each is linked with ZNF611 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF611-to-partner and partner-to-ZNF611 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF611→partner) and Y-score (partner→ZNF611) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.375	+1.784	.003	<.001	3	4
UCEC	TAF9 →	+0.502	+1.784	<.001	<.001	3	3
UCEC	CCDC3 →	-0.565	-1.652	.005	.005	3	3
SKCM	RRP36 →	+0.461	+3.207	.003	.009	3	3
UCEC	PHF5A →	+0.464	+1.784	<.001	<.001	3	3
UCEC	OIP5 →	+0.689	+1.805	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,707 associations by consensus.

Exploration

ZNF611 survival (RNA) · tumor vs normal (RNA) · all ZNF611 data types