Across TCGA cell cohorts, ZNF611 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF611-associated genes across cancer lineages are KNCN, FBXO40, and TRIM77. Each is linked with ZNF611 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF611-to-partner and partner-to-ZNF611 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF611→partner) and Y-score (partner→ZNF611) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	KNCN →	+0.229	+4.108	.004	.005	3	1
LUNG_NSCLC_LUSC	FBXO40 →	+0.077	+4.108	.001	.005	3	1
LUNG_NSCLC_LUSC	TRIM77 →	+0.055	+4.584	<.001	.001	3	1
LUNG_NSCLC_LUSC	OR52E5 →	+0.011	+4.108	.009	.005	3	1
LUNG_SCLC	SEMG1 →	+0.015	+4.169	<.001	.001	3	1
LUNG_SCLC	IL36A →	+0.016	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

ZNF611 survival (RNA) · tumor vs normal (RNA) · all ZNF611 data types